KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
30
Human Site:
Y420
Identified Species:
44
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
Y420
I
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
Chimpanzee
Pan troglodytes
XP_520198
559
62217
Y457
I
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
Y419
I
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
Dog
Lupus familis
XP_532038
521
58332
Y419
I
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
Y419
I
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
Rat
Rattus norvegicus
Q5BK30
415
45841
T314
L
D
S
C
F
D
Y
T
G
K
L
I
A
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
H289
N
F
S
P
N
G
Y
H
I
A
T
G
S
G
D
Chicken
Gallus gallus
Q5ZMA2
505
55116
N404
T
S
I
A
F
S
E
N
G
Y
Y
L
A
T
A
Frog
Xenopus laevis
Q5FWQ6
415
45899
T314
L
D
V
T
F
D
S
T
G
Q
L
V
A
T
A
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
T314
L
D
V
C
F
N
Y
T
G
Q
L
I
A
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
G309
N
K
K
G
H
H
Q
G
P
F
L
A
S
G
S
Honey Bee
Apis mellifera
XP_393186
525
59172
F421
I
D
F
S
P
N
G
F
H
I
A
T
A
S
E
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
N391
R
S
I
A
F
S
E
N
G
Y
Y
L
A
T
G
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
Y400
V
N
F
S
P
N
G
Y
Q
L
A
T
G
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
Y436
V
N
F
S
P
N
G
Y
H
L
A
S
G
G
E
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
V364
W
S
P
N
G
Y
Q
V
A
T
G
G
G
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
0
0
6.6
N.A.
0
73.3
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
6.6
26.6
33.3
26.6
N.A.
6.6
86.6
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
7
7
50
7
38
0
25
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
0
13
0
0
0
0
0
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
19
% E
% Phe:
0
7
50
0
32
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
7
50
7
32
0
7
13
50
19
44
% G
% His:
0
0
0
0
7
7
0
7
44
0
0
0
0
0
0
% H
% Ile:
38
0
13
0
0
0
0
0
7
38
0
13
0
0
0
% I
% Lys:
0
7
7
0
0
0
0
0
0
7
0
0
0
0
0
% K
% Leu:
19
0
0
0
0
0
0
0
0
13
25
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
44
0
7
7
57
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
7
50
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
7
13
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
13
50
0
13
7
0
0
0
0
7
13
44
7
% S
% Thr:
7
0
0
7
0
0
0
19
0
7
7
44
0
32
0
% T
% Val:
13
0
13
0
0
0
0
7
0
0
0
7
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
19
44
0
13
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _